dissertation/app1-supplementary.qmd at main · Aastedet/dissertation · GitHub

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# Supplementary validation analyses {#sec-nhs-validation}

### Validation of unspecified diabetes in the Health In Central Denmark survey and in the National Health Survey.

Validation analyses performed in the HICD study population from study I:

::: {#tbl-sup-dm-hicd layout-ncol="1"}
| **OSDC**        | **Survey: +DM**      | **Survey: -DM** | **Total N** |
|-----------------|----------------------|-----------------|-------------|
| **OSDC: +DM**   | 2,512                | 221             | 2,733       |
| **OSDC: -DM**   | 121                  | 26,537          | 26,658      |
| **Total N**     | 2,633                | 26,758          | 29,391      |
| **Sensitivity** | 0.954 (0.945, 0.962) |                 |             |
| **Specificity** | 0.992 (0.991, 0.993) |                 |             |
| **PPV**         | 0.919 (0.908, 0.929) |                 |             |
| **NPV**         | 0.995 (0.995, 0.996) |                 |             |

: The Open-Source Diabetes Classifier (OSDC)

| **RSCD**        | **Survey: +DM**      | **Survey: -DM** | **Total N** |
|-----------------|----------------------|-----------------|-------------|
| **RSCD: +DM**   | 2,422                | 122             | 2,544       |
| **RSCD: -DM**   | 211                  | 26,636          | 26,847      |
| **Total N**     | 2,633                | 26,758          | 29,391      |
| **Sensitivity** | 0.920 (0.909, 0.930) |                 |             |
| **Specificity** | 0.995 (0.995, 0.996) |                 |             |
| **PPV**         | 0.952 (0.943, 0.960) |                 |             |
| **NPV**         | 0.992 (0.991, 0.993) |                 |             |

: The Register for Selected Chronic Diseases (RSCD)

**Supplementary: Validation of uspecified diabetes in the HICD study population**
:::

Validation analyses performed among respondents in the National Health Survey 2017 (individuals reporting diabetes as a current disease were considered diabetes cases).

::: {#tbl-sup-dm-nhs layout-ncol="1"}
| **OSDC**        | **Survey: +DM**   | **Survey: -DM** | **Total N** |
|-----------------|-------------------|-----------------|-------------|
| **OSDC: +DM**   | 1,630             | 258             | 1,888       |
| **OSDC: -DM**   | 87                | 26,460          | 26,547      |
| **Total N**     | 1,717             | 26,718          | 28,435      |
| **Sensitivity** | 0.95 (0.94, 0.96) |                 |             |
| **Specificity** | 0.99 (0.99, 0.99) |                 |             |
| **PPV**         | 0.86 (0.85, 0.88) |                 |             |
| **NPV**         | 1.00 (1.00, 1.00) |                 |             |

: The Open-Source Diabetes Classifier (OSDC)

| **RSCD**        | **Survey: +DM**   | **Survey: -DM** | **Total N** |
|-----------------|-------------------|-----------------|-------------|
| **RSCD: +DM**   | 1,546             | 184             | 1,730       |
| **RSCD: -DM**   | 171               | 26,534          | 26,705      |
| **Total N**     | 1,717             | 26,718          | 28,435      |
| **Sensitivity** | 0.90 (0.89, 0.91) |                 |             |
| **Specificity** | 0.99 (0.99, 0.99) |                 |             |
| **PPV**         | 0.89 (0.88, 0.91) |                 |             |
| **NPV**         | 0.99 (0.99, 0.99) |                 |             |

: The Register for Selected Chronic Diseases (RSCD)

**Supplementary: Validation of uspecified diabetes in the National Health Survey**
:::

::: {.content-visible when-format="pdf"}
# Full papers {#sec-papers}

## Paper I

\newpage

## Paper II

\newpage

## Paper III
:::