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| 1 | +import { OptionsModel } from './options.model'; |
| 2 | +import {RowsModel} from './rows.model'; |
| 3 | +import {ColorsModel} from './colors.model'; |
| 4 | +import {Log} from './log.model'; |
| 5 | +import {SelectionModel} from './selection.model'; |
| 6 | +import {IconsModel} from './icons.model'; |
| 7 | +import {SequenceInfoModel} from './sequenceInfoModel'; |
| 8 | +import {EventsModel} from './events.model'; |
| 9 | +import {PatternsModel} from './patterns.model'; |
| 10 | +import {InputModel} from './input.model'; |
| 11 | +import {ConsensusModel} from './consensus.model'; |
| 12 | + |
| 13 | +export class SequenceViewer { |
| 14 | + static sqvList = []; |
| 15 | + divId: string; |
| 16 | + init: boolean; |
| 17 | + input: InputModel; |
| 18 | + params: OptionsModel; |
| 19 | + rows: RowsModel; |
| 20 | + consensus: ConsensusModel; |
| 21 | + regions: ColorsModel; |
| 22 | + patterns: PatternsModel; |
| 23 | + icons: IconsModel; |
| 24 | + labels: SequenceInfoModel; |
| 25 | + selection: SelectionModel; |
| 26 | + events: EventsModel; |
| 27 | + |
| 28 | + constructor(divId?: string ) { |
| 29 | + this.divId = divId; |
| 30 | + this.init = false; |
| 31 | + this.input = new InputModel(); |
| 32 | + this.params = new OptionsModel(); |
| 33 | + this.rows = new RowsModel(); |
| 34 | + this.consensus = new ConsensusModel(); |
| 35 | + this.regions = new ColorsModel(); |
| 36 | + this.patterns = new PatternsModel(); |
| 37 | + this.icons = new IconsModel(); |
| 38 | + this.labels = new SequenceInfoModel(); |
| 39 | + this.selection = new SelectionModel(); |
| 40 | + this.events = new EventsModel(); |
| 41 | + |
| 42 | + window.onresize = () => { |
| 43 | + for (const id of SequenceViewer.sqvList) { |
| 44 | + |
| 45 | + const sqvBody = document.getElementById(id); |
| 46 | + if (!sqvBody) { Log.w(1, 'Cannot find sqv-body element.'); continue; } |
| 47 | + |
| 48 | + const chunks = sqvBody.getElementsByClassName('cnk'); |
| 49 | + if (!chunks) { Log.w(1, 'Cannot find chunk elements.'); continue; } |
| 50 | + |
| 51 | + let oldTop = 0; |
| 52 | + let newTop; |
| 53 | + // tslint:disable-next-line:prefer-for-of |
| 54 | + for (let i = 0; i < chunks.length; i++) { |
| 55 | + newTop = chunks[i].getBoundingClientRect().top; |
| 56 | + if (chunks[i].getBoundingClientRect().top == 0) { |
| 57 | + newTop = chunks[i].getBoundingClientRect().height |
| 58 | + } |
| 59 | + |
| 60 | + if (newTop > oldTop) { |
| 61 | + chunks[i].firstElementChild.className = 'idx'; |
| 62 | + oldTop = newTop; |
| 63 | + } else { |
| 64 | + chunks[i].firstElementChild.className = 'idx hidden'; |
| 65 | + } |
| 66 | + } |
| 67 | + } |
| 68 | + }; |
| 69 | + } |
| 70 | + |
| 71 | + public draw(input1?, input2?, input3?, input4?, input5?, input6?, input7?) { |
| 72 | + |
| 73 | + SequenceViewer.sqvList.push(this.divId); |
| 74 | + |
| 75 | + let inputs; |
| 76 | + let order; |
| 77 | + let labels; |
| 78 | + let startIndexes; |
| 79 | + let tooltips; |
| 80 | + let data; |
| 81 | + |
| 82 | + /** check and process input */ |
| 83 | + [inputs, order] = this.input.process(input1, input2, input3, input4, input5, input6, input7); |
| 84 | + |
| 85 | + /** check and process parameters input */ |
| 86 | + inputs.options = this.params.process(inputs.options); |
| 87 | + |
| 88 | + /** check and consensus input and global colorScheme */ |
| 89 | + [inputs.sequences, inputs.regions, order ] = this.consensus.process(inputs.sequences, inputs.regions, inputs.options, order); |
| 90 | + |
| 91 | + |
| 92 | + /** check and process patterns input */ |
| 93 | + inputs.patterns = this.patterns.process(inputs.patterns, inputs.sequences); |
| 94 | + |
| 95 | + /** check and process colors input */ |
| 96 | + inputs.regions = this.regions.process(inputs, order); |
| 97 | + |
| 98 | + /** check and process icons input */ |
| 99 | + inputs.icons = this.icons.process(inputs.regions, inputs.sequences, inputs.iconsHtml, inputs.iconsPaths); |
| 100 | + |
| 101 | + /** check and process sequences input */ |
| 102 | + data = this.rows.process(inputs.sequences, inputs.icons, inputs.regions, inputs.options.colorScheme); |
| 103 | + |
| 104 | + /** check and process labels input */ |
| 105 | + [ labels, startIndexes, tooltips ] = this.labels.process(inputs.regions, inputs.sequences); |
| 106 | + |
| 107 | + /** create/update sqv-body html */ |
| 108 | + this.createGUI(data, labels, startIndexes, tooltips, inputs.options); |
| 109 | + |
| 110 | + /** listen copy paste events */ |
| 111 | + this.selection.process(); |
| 112 | + |
| 113 | + /** listen selection events */ |
| 114 | + this.events.onRegionSelected(); |
| 115 | + } |
| 116 | + |
| 117 | + private generateLabels(idx, labels, startIndexes, topIndexes, chunkSize, fontSize, tooltips, data, rowMarginBottom) { |
| 118 | + let labelshtml = ''; |
| 119 | + let labelsContainer = ''; |
| 120 | + const noGapsLabels = []; |
| 121 | + |
| 122 | + if (labels.length > 0) { |
| 123 | + if (topIndexes) { |
| 124 | + labelshtml += `<span class="lbl-hidden" style="margin-bottom:${rowMarginBottom};"></span>`; |
| 125 | + } |
| 126 | + let flag; |
| 127 | + let count = -1; |
| 128 | + let seqN = -1; |
| 129 | + for (const seqNum of data) { |
| 130 | + if (noGapsLabels.length < data.length) { |
| 131 | + noGapsLabels.push(0); |
| 132 | + } |
| 133 | + seqN += 1; |
| 134 | + for (const res in seqNum) { |
| 135 | + if (seqNum[res].char && seqNum[res].char.includes('svg')) { |
| 136 | + flag = true; |
| 137 | + break; |
| 138 | + } |
| 139 | + } |
| 140 | + |
| 141 | + if (flag) { |
| 142 | + noGapsLabels[seqN] = ''; |
| 143 | + if (idx) { |
| 144 | + // line with only icons, no need for index |
| 145 | + labelshtml += `<span class="lbl-hidden" style="margin-bottom:${rowMarginBottom}"><span class="lbl"> ${noGapsLabels[seqN]}</span></span>`; |
| 146 | + } else { |
| 147 | + labelshtml += `<span class="lbl-hidden" style="margin-bottom:${rowMarginBottom}"><span class="lbl"></span></span>`; |
| 148 | + } |
| 149 | + |
| 150 | + } else { |
| 151 | + count += 1; |
| 152 | + if (idx) { |
| 153 | + if (!chunkSize) { |
| 154 | + // lateral index regular |
| 155 | + labelshtml += `<span class="lbl-hidden" style="width: ${fontSize};margin-bottom:${rowMarginBottom}"> |
| 156 | + <span class="lbl" >${(startIndexes[count] - 1) + idx}</span></span>`; |
| 157 | + } else { |
| 158 | + let noGaps = 0; |
| 159 | + for (const res in seqNum) { |
| 160 | + if (+res <= (idx) && seqNum[res].char !== '-') { |
| 161 | + noGaps += 1; |
| 162 | + } |
| 163 | + } |
| 164 | + // lateral index gap |
| 165 | + noGapsLabels[seqN] = noGaps; |
| 166 | + labelshtml += `<span class="lbl-hidden" style="width: ${fontSize};margin-bottom:${rowMarginBottom}"> |
| 167 | + <span class="lbl" >${(startIndexes[count] - 1) + noGapsLabels[seqN]}</span></span>`; |
| 168 | + } |
| 169 | + |
| 170 | + } else { |
| 171 | + labelshtml += `<span class="lbl-hidden" style="margin-bottom:${rowMarginBottom}"><span class="lbl">${labels[count]}${tooltips[count]}</span></span>`; |
| 172 | + } |
| 173 | + } |
| 174 | + flag = false; |
| 175 | + } |
| 176 | + |
| 177 | + labelsContainer = `<span class="lblContainer" style="display: inline-block">${labelshtml}</span>`; |
| 178 | + } |
| 179 | + return labelsContainer; |
| 180 | + } |
| 181 | + |
| 182 | + private addTopIndexes(topIndexes, chunkSize, x, maxTop, rowMarginBottom) { |
| 183 | + |
| 184 | + let cells = ''; |
| 185 | + // adding top indexes |
| 186 | + if (topIndexes) { |
| 187 | + let chunkTopIndex; |
| 188 | + if (x % chunkSize === 0 && x <= maxTop) { |
| 189 | + chunkTopIndex = `<span class="cell" style="-webkit-user-select: none;direction: rtl;display:block;width:0.6em;margin-bottom:${rowMarginBottom}">${x}</span>`; |
| 190 | + |
| 191 | + } else { |
| 192 | + chunkTopIndex = `<span class="cell" style="-webkit-user-select: none;display:block;visibility: hidden;margin-bottom:${rowMarginBottom}">0</span>`; |
| 193 | + } |
| 194 | + cells += chunkTopIndex; |
| 195 | + } |
| 196 | + return cells; |
| 197 | + } |
| 198 | + |
| 199 | + private createGUI(data, labels, startIndexes, tooltips, options) { |
| 200 | + |
| 201 | + const sqvBody = document.getElementById(this.divId); |
| 202 | + |
| 203 | + if (!sqvBody) { |
| 204 | + Log.w(1, 'Cannot find sqv-body element.'); |
| 205 | + return; |
| 206 | + } |
| 207 | + |
| 208 | + const chunkSize = options.chunkSize; |
| 209 | + const fontSize = options.fontSize; |
| 210 | + const spaceSize = options.spaceSize; |
| 211 | + const topIndexes = options.topIndexes; |
| 212 | + const lateralIndexesGap = options.lateralIndexesGap; |
| 213 | + const oneLineSetting = options.oneLineSetting; |
| 214 | + const oneLineWidth = options.oneLineWidth; |
| 215 | + const rowMarginBottom = options.rowMarginBottom + ';'; |
| 216 | + const fNum = +fontSize.substr(0, fontSize.length - 2); |
| 217 | + const fUnit = fontSize.substr(fontSize.length - 2, 2); |
| 218 | + |
| 219 | + |
| 220 | + |
| 221 | + // maxIdx = length of the longest sequence |
| 222 | + let maxIdx = 0; |
| 223 | + let maxTop = 0; |
| 224 | + for (const row of data) { |
| 225 | + if (maxIdx < Object.keys(row).length) { maxIdx = Object.keys(row).length; } |
| 226 | + if (maxTop < Object.keys(row).length) { maxTop = Object.keys(row).length; } |
| 227 | + } |
| 228 | + |
| 229 | + const lenghtIndex = maxIdx.toString().length; |
| 230 | + const indexWidth = (fNum * lenghtIndex).toString() + fUnit; |
| 231 | + |
| 232 | + // consider the last chunk even if is not long enough |
| 233 | + if (chunkSize > 0) { maxIdx += (chunkSize - (maxIdx % chunkSize)) % chunkSize; } |
| 234 | + |
| 235 | + // generate labels |
| 236 | + const labelsContainer = this.generateLabels(false, labels, startIndexes, topIndexes, false, indexWidth, tooltips, data, rowMarginBottom); |
| 237 | + |
| 238 | + let index = ''; |
| 239 | + let cards = ''; |
| 240 | + let cell; |
| 241 | + let entity; |
| 242 | + let style; |
| 243 | + let html = ''; |
| 244 | + let idxNum = 0; |
| 245 | + let idx; |
| 246 | + |
| 247 | + for (let x = 1; x <= maxIdx; x++) { |
| 248 | + let cells = this.addTopIndexes(topIndexes, chunkSize, x, maxTop, rowMarginBottom); |
| 249 | + |
| 250 | + for (let y = 0; y < data.length; y++) { |
| 251 | + entity = data[y][x]; |
| 252 | + style = 'font-size: 1em;display:block;height:1em;line-height:1em;margin-bottom:' + rowMarginBottom; |
| 253 | + if (y === data.length - 1) { style = 'font-size: 1em;display:block;line-height:1em;margin-bottom:' + rowMarginBottom; } |
| 254 | + if (!entity) { |
| 255 | + // emptyfiller |
| 256 | + cell = `<span style="${style}"> </span>`; |
| 257 | + } else { |
| 258 | + if (entity.target) { style += `${entity.target}`; } |
| 259 | + if (entity.char && !entity.char.includes('svg')) { |
| 260 | + // y is the row, x is the column |
| 261 | + cell = `<span class="cell" data-res-x='${x}' data-res-y= '${y}' data-res-id= '${this.divId}' |
| 262 | + style="${style}">${entity.char}</span>`; |
| 263 | + } else { |
| 264 | + style += '-webkit-user-select: none;'; |
| 265 | + cell = `<span style="${style}">${entity.char}</span>`; |
| 266 | + } |
| 267 | + } |
| 268 | + cells += cell; |
| 269 | + } |
| 270 | + |
| 271 | + cards += `<div class="crd">${cells}</div>`; // width 3/5em to reduce white space around letters |
| 272 | + cells = ''; |
| 273 | + |
| 274 | + |
| 275 | + if (chunkSize > 0 && x % chunkSize === 0) { |
| 276 | + // considering the row of top indexes |
| 277 | + if (topIndexes) { |
| 278 | + } else { |
| 279 | + idxNum += chunkSize; // lateral index (set only if top indexes missing) |
| 280 | + idx = idxNum - (chunkSize - 1); |
| 281 | + } |
| 282 | + // adding labels |
| 283 | + if (lateralIndexesGap && !topIndexes) { |
| 284 | + const gapsContainer = this.generateLabels(idx, labels, startIndexes, topIndexes, false, indexWidth, false, data, rowMarginBottom); |
| 285 | + if (oneLineSetting) { |
| 286 | + index = gapsContainer; // lateral number indexes + labels |
| 287 | + } else { |
| 288 | + index = labelsContainer + gapsContainer; // lateral number indexes + labels |
| 289 | + } |
| 290 | + |
| 291 | + } else if (!lateralIndexesGap && !topIndexes) { |
| 292 | + const gapsContainer = this.generateLabels(idx, labels, startIndexes, topIndexes, chunkSize, indexWidth, false, data, rowMarginBottom); |
| 293 | + if (oneLineSetting) { |
| 294 | + index = gapsContainer; // lateral number indexes + labels |
| 295 | + } else { |
| 296 | + index = labelsContainer + gapsContainer; // lateral number indexes + labels |
| 297 | + } |
| 298 | + } else { |
| 299 | + index = labelsContainer; |
| 300 | + } |
| 301 | + |
| 302 | + index = `<div class="idx hidden">${index}</div>`; |
| 303 | + style = `font-size: ${fontSize};`; |
| 304 | + |
| 305 | + if (x !== maxIdx) { style += 'padding-right: ' + spaceSize + 'em;'; } else { style += 'margin-right: ' + spaceSize + 'em;'; } |
| 306 | + |
| 307 | + const chunk = `<div class="cnk" style="${style}">${index}<div class="crds">${cards}</div></div>`; |
| 308 | + cards = ''; |
| 309 | + index = ''; |
| 310 | + html += chunk; |
| 311 | + } |
| 312 | + } |
| 313 | + |
| 314 | + if (oneLineSetting) { |
| 315 | + sqvBody.innerHTML = `<div class="root" style="display: flex"><div style="${style}">${labelsContainer}</div> |
| 316 | + <div style="display:inline-block;overflow-x:scroll;white-space: nowrap;width:${oneLineWidth}"> ${html}</div></div>`; |
| 317 | + } else { |
| 318 | + sqvBody.innerHTML = `<div class="root">${html}</div>`; |
| 319 | + } |
| 320 | + |
| 321 | + window.dispatchEvent(new Event('resize')); |
| 322 | + } |
| 323 | +} |
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