|
| 1 | +# TODO move this to tutorial |
| 2 | +# TODO polish this |
| 3 | +import datetime |
| 4 | + |
| 5 | +from auxiliary.normalization.percentile_normalizer import PercentileNormalizer |
| 6 | +from auxiliary.turbopath import turbopath |
| 7 | +from tqdm import tqdm |
| 8 | + |
| 9 | +from brainles_preprocessing.brain_extraction import HDBetExtractor |
| 10 | +from brainles_preprocessing.modality import Modality |
| 11 | +from brainles_preprocessing.preprocessor import Preprocessor |
| 12 | +from brainles_preprocessing.registration import NiftyRegRegistrator |
| 13 | + |
| 14 | + |
| 15 | +def preprocess(inputDir): |
| 16 | + inputDir = turbopath(inputDir) |
| 17 | + try: |
| 18 | + print("*** start ***") |
| 19 | + |
| 20 | + # where are the raw mr files? |
| 21 | + btk_raw_dir = turbopath(inputDir) |
| 22 | + |
| 23 | + # is the exam already processed? |
| 24 | + brainles_dir = turbopath(inputDir) + "/" + inputDir.name + "_brainles" |
| 25 | + raw_bet_dir = brainles_dir / "raw_bet" |
| 26 | + norm_bet_dir = brainles_dir / "normalized_bet" |
| 27 | + raw_skull_dir = brainles_dir / "raw_skull" |
| 28 | + norm_skull_dir = brainles_dir / "normalized_skull" |
| 29 | + |
| 30 | + # if not os.path.exists(prep_dir): |
| 31 | + # if os.path.exists(prep_dir): |
| 32 | + t1_file = btk_raw_dir.files("*t1.nii.gz") |
| 33 | + t1c_file = btk_raw_dir.files("*t1c.nii.gz") |
| 34 | + t2_file = btk_raw_dir.files("*t2.nii.gz") |
| 35 | + flair_file = btk_raw_dir.files("*fla.nii.gz") |
| 36 | + |
| 37 | + if len(t1_file) == len(t1c_file) == len(t2_file) == len(flair_file) == 1: |
| 38 | + # print(t1_file) |
| 39 | + # print(t1c_file) |
| 40 | + # print(t2_file) |
| 41 | + # print(flair_file) |
| 42 | + |
| 43 | + t1File = t1_file[0] |
| 44 | + t1cFile = t1c_file[0] |
| 45 | + t2File = t2_file[0] |
| 46 | + flaFile = flair_file[0] |
| 47 | + |
| 48 | + # normalizer |
| 49 | + percentile_normalizer = PercentileNormalizer( |
| 50 | + lower_percentile=0.1, |
| 51 | + upper_percentile=99.9, |
| 52 | + lower_limit=0, |
| 53 | + upper_limit=1, |
| 54 | + ) |
| 55 | + |
| 56 | + # define modalities |
| 57 | + center = Modality( |
| 58 | + modality_name="t1c", |
| 59 | + input_path=t1cFile, |
| 60 | + raw_bet_output_path=raw_bet_dir / inputDir.name + "_t1c_bet_raw.nii.gz", |
| 61 | + raw_skull_output_path=raw_skull_dir / inputDir.name |
| 62 | + + "_t1c_skull_raw.nii.gz", |
| 63 | + normalized_bet_output_path=norm_bet_dir / inputDir.name |
| 64 | + + "_t1c_bet_normalized.nii.gz", |
| 65 | + normalized_skull_output_path=norm_skull_dir / inputDir.name |
| 66 | + + "_t1c_skull_normalized.nii.gz", |
| 67 | + atlas_correction=True, |
| 68 | + normalizer=percentile_normalizer, |
| 69 | + ) |
| 70 | + |
| 71 | + moving_modalities = [ |
| 72 | + Modality( |
| 73 | + modality_name="t1", |
| 74 | + input_path=t1File, |
| 75 | + raw_bet_output_path=raw_bet_dir / inputDir.name |
| 76 | + + "_t1_bet_raw.nii.gz", |
| 77 | + raw_skull_output_path=raw_skull_dir / inputDir.name |
| 78 | + + "_t1_skull_raw.nii.gz", |
| 79 | + normalized_bet_output_path=norm_bet_dir / inputDir.name |
| 80 | + + "_t1_bet_normalized.nii.gz", |
| 81 | + normalized_skull_output_path=norm_skull_dir / inputDir.name |
| 82 | + + "_t1_skull_normalized.nii.gz", |
| 83 | + atlas_correction=True, |
| 84 | + normalizer=percentile_normalizer, |
| 85 | + ), |
| 86 | + Modality( |
| 87 | + modality_name="t2", |
| 88 | + input_path=t2File, |
| 89 | + raw_bet_output_path=raw_bet_dir / inputDir.name |
| 90 | + + "_t2_bet_raw.nii.gz", |
| 91 | + raw_skull_output_path=raw_skull_dir / inputDir.name |
| 92 | + + "_t2_skull_raw.nii.gz", |
| 93 | + normalized_bet_output_path=norm_bet_dir / inputDir.name |
| 94 | + + "_t2_bet_normalized.nii.gz", |
| 95 | + normalized_skull_output_path=norm_skull_dir / inputDir.name |
| 96 | + + "_t2_skull_normalized.nii.gz", |
| 97 | + atlas_correction=True, |
| 98 | + normalizer=percentile_normalizer, |
| 99 | + ), |
| 100 | + Modality( |
| 101 | + modality_name="flair", |
| 102 | + input_path=flaFile, |
| 103 | + raw_bet_output_path=raw_bet_dir / inputDir.name |
| 104 | + + "_fla_bet_raw.nii.gz", |
| 105 | + raw_skull_output_path=raw_skull_dir / inputDir.name |
| 106 | + + "_fla_skull_raw.nii.gz", |
| 107 | + normalized_bet_output_path=norm_bet_dir / inputDir.name |
| 108 | + + "_fla_bet_normalized.nii.gz", |
| 109 | + normalized_skull_output_path=norm_skull_dir / inputDir.name |
| 110 | + + "_fla_skull_normalized.nii.gz", |
| 111 | + atlas_correction=True, |
| 112 | + normalizer=percentile_normalizer, |
| 113 | + ), |
| 114 | + ] |
| 115 | + |
| 116 | + preprocessor = Preprocessor( |
| 117 | + center_modality=center, |
| 118 | + moving_modalities=moving_modalities, |
| 119 | + registrator=NiftyRegRegistrator(), |
| 120 | + brain_extractor=HDBetExtractor(), |
| 121 | + temp_folder="tempo", |
| 122 | + limit_cuda_visible_devices="1", |
| 123 | + ) |
| 124 | + |
| 125 | + preprocessor.run( |
| 126 | + save_dir_coregistration=brainles_dir + "/co-registration", |
| 127 | + save_dir_atlas_registration=brainles_dir + "/atlas-registration", |
| 128 | + save_dir_atlas_correction=brainles_dir + "/atlas-correction", |
| 129 | + save_dir_brain_extraction=brainles_dir + "/brain-extraction", |
| 130 | + ) |
| 131 | + |
| 132 | + except Exception as e: |
| 133 | + print("error: " + str(e)) |
| 134 | + print("conversion error for:", inputDir) |
| 135 | + |
| 136 | + time = str(datetime.datetime.now().time()) |
| 137 | + |
| 138 | + print("** finished:", inputDir.name, "at:", time) |
| 139 | + |
| 140 | + |
| 141 | +### *** GOGOGO *** ### |
| 142 | +if __name__ == "__main__": |
| 143 | + EXAMPLE_DATA_DIR = turbopath("example/example_data") |
| 144 | + |
| 145 | + exams = EXAMPLE_DATA_DIR.dirs() |
| 146 | + |
| 147 | + for exam in tqdm(exams): |
| 148 | + print("processing:", exam) |
| 149 | + preprocess(exam) |
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