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25 | 25 | \theoremstyle{thmstylethree} |
26 | 26 | \newtheorem{definition}{Definition} |
27 | 27 |
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| 28 | +\providecommand{\authormark}[1]{\gdef\@authormark{#1}} |
28 | 29 | \begin{document} |
29 | 30 |
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30 | 31 | % ── Journal metadata ───────────────────────────────────────────────────────── |
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37 | 38 | \firstpage{1} |
38 | 39 |
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39 | 40 | % ── Title ──────────────────────────────────────────────────────────────────── |
40 | | -\title[Graph Lens Lite]{Graph Lens Lite: An interactive biological network viewer for displaying, sharing, and exploring disease pathobiology and drug mechanism of action models} |
| 41 | +\title{Graph Lens Lite: An interactive biological network viewer for displaying, exploring, and sharing disease pathobiology and drug mechanism of action models} |
41 | 42 |
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42 | 43 | % ── Authors & affiliations ─────────────────────────────────────────────────── |
43 | 44 | \author[1,2,$\ast$]{Matthias Ley\ORCID{0000-0001-6853-8542}} |
44 | 45 | \author[1]{Kinga Kęska-Izworska\ORCID{0000-0002-4329-1499}} |
45 | 46 | \author[1]{Lucas Fillinger\ORCID{0000-0001-5341-8097}} |
46 | | -\author[1]{Samuel Walter} |
| 47 | +\author[1]{Samuel M Walter} |
| 48 | +\author[1]{Fabio Baumg\"{a}rtel} |
47 | 49 | \author[1,2]{Enrico Bono\ORCID{0009-0007-7272-5034}} |
48 | 50 | \author[1,2]{Louiza Galou\ORCID{0009-0008-5176-2802}} |
49 | 51 | \author[1]{Peter Andorfer\ORCID{0009-0003-3492-4017}} |
50 | 52 | \author[3]{Pirmin Hauser} |
51 | 53 | \author[3]{Johannes Leierer} |
52 | | -\author[1,2]{Klaus Kratochwill\ORCID{0000-0003-0803-614X}} |
53 | | -\author[1,3]{Paul Perco\ORCID{0000-0003-2087-5691}} |
| 54 | +\author[1,2,$\#$,$\ast$]{Klaus Kratochwill\ORCID{0000-0003-0803-614X}} |
| 55 | +\author[1,3,$\#$]{Paul Perco\ORCID{0000-0003-2087-5691}} |
54 | 56 |
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55 | 57 | \authormark{Ley et al.} |
56 | 58 |
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57 | | -\address[1]{\orgname{Delta4 GmbH}, \orgaddress{\street{Alser Straße 23/30}, \postcode{1080}, \state{Vienna}, \country{Austria}}} |
| 59 | +\address[1]{\orgname{Delta4 GmbH}, \orgaddress{\street{Alser Stra\ss{}e 23/30}, \postcode{1080}, \state{Vienna}, \country{Austria}}} |
58 | 60 | \address[2]{\orgdiv{Division of Pediatric Nephrology and Gastroenterology, Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics}, \orgname{Medical University Vienna}, \orgaddress{\street{Waehringer Guertel 18-20}, \postcode{1090}, \state{Vienna}, \country{Austria}}} |
59 | | -\address[4]{\orgdiv{Department of Internal Medicine IV}, \orgname{Medical University Innsbruck}, \orgaddress{\street{Anichstrasse 35}, \postcode{6020}, \state{Innsbruck}, \country{Austria}}} |
| 61 | +\address[3]{\orgdiv{Department of Internal Medicine IV}, \orgname{Medical University Innsbruck}, \orgaddress{\street{Anichstrasse 35}, \postcode{6020}, \state{Innsbruck}, \country{Austria}}} |
60 | 62 |
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61 | | -\corresp[$\ast$]{Corresponding author. \href{email:matthias.ley@delta4.ai}{matthias.ley@delta4.ai}} |
| 63 | +\corresp[$\ast$]{Corresponding authors. \href{mailto:matthias.ley@delta4.ai}{matthias.ley@delta4.ai}, \href{mailto:klaus.kratochwill@delta4.ai}{klaus.kratochwill@delta4.ai}\\} |
| 64 | + |
| 65 | +\corresp[$\#$]{Contributed equally} |
62 | 66 |
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63 | 67 | \received{Date}{0}{Year} |
64 | 68 | \revised{Date}{0}{Year} |
65 | 69 | \accepted{Date}{0}{Year} |
66 | 70 |
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67 | 71 | % ── Abstract ───────────────────────────────────────────────────────────────── |
68 | | -\abstract{ |
69 | | -\textbf{Motivation:} Biological networks are important .. \\ |
70 | | -\textbf{Results:} We have developed Graph Lens Lite, a lightweight but powerful interactive network viewer for displaying, sharing, and exploring disease pathobiology and drug mechanism of action molecular models. … \\ |
71 | | -\textbf{Availability and implementation:} Graph Lens Lite is available at GitHub (\url{https://github.com/Delta4AI/GraphLensLite}).\\ |
| 72 | +\abstract{\mdseries |
| 73 | +\textbf{Motivation:} Biological network visualization together with graph-based analyses are key techniques in systems biology and network medicine to detect patterns and generate new hypotheses regarding disease pathobiology, drug target identification, or digital drug discovery. Network representations are also a way to communicate research findings and share results with colleagues and coworkers. \\ |
| 74 | +\textbf{Results:} We have developed Graph Lens Lite, a browser-based tool that combines rich visualization capabilities with a streamlined interface for exploring and sharing biological networks. It offers an expressive query language, topological network analysis, GUI-based filtering, visual grouping, customizable layouts, a data-editor, and fine-grained property-based styling options, particularly suited for visualizing molecular models of disease pathobiology or drug mechanism of action. \\ |
| 75 | +\textbf{Availability:} Graph Lens Lite is available at GitHub (\url{https://github.com/Delta4AI/GraphLensLite}).\\ |
72 | 76 | \textbf{Contact:} \href{mailto:matthias.ley@delta4.ai}{matthias.ley@delta4.ai}\\ |
73 | | -\textbf{Supplementary information:} Supplementary data are available at \textit{Bioinformatics} |
74 | | -online. |
| 77 | +\textbf{Supplementary information:} Supplementary data are available at \textit{Bioinformatics} online. |
75 | 78 | } |
76 | 79 |
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77 | | -\keywords{Network Viewer, Graph Exploration, Visualization, Drug Mechanism of Action, Disease Pathobiology} |
| 80 | +\keywords{network visualization, graph exploration, disease pathobiology, drug mechanism of action} |
78 | 81 |
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79 | 82 | \maketitle |
80 | 83 |
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