update

Author: WPZgithub

ground_truths/driver_regulators/ESC_Cell2011.csv

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+TFs,TFs_ori,TFs_mouse,Function
+POU5F1,4-Oct,Pou5f1,Core circuitry
+SOX2,Sox2,Sox2,Core circuitry
+NANOG,Nanog,Nanog,Core circuitry
+TCF3,Tcf3,Tcf3,Wnt signaling to core circuitry
+STAT3,Stat3,Stat3,Lif signaling to core circuitry
+SMAD1,Smad1,Smad1,BMP signaling to core circuitry
+SMAD2,Smad2,Smad2,TGF-¦Â/Activin/Nodal signaling
+SMAD3,Smad3,Smad3,TGF-¦Â/Activin/Nodal signaling
+MYC,c-Myc,Myc,Proliferation
+ESRRB,Esrrb,Esrrb,Steroid hormone receptor
+SALL4,Sall4,Sall4,Embryonic regulator
+TBX3,Tbx3,Tbx3,Mediates LIF signaling
+ZFX,Zfx,Zfx,Self-renewal
+THAP11,Ronin,Thap11,Metabolism
+KLF4,Klf4,Klf4,LIF signaling
+PRDM14,Prdm14,Prdm14,ESC identity

ground_truths/driver_regulators/ESC_Reproduction2008.csv

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+TFs,TFs_ori,TFs_mouse,description
+POU5F1,OCT3B/4,Pou5f1,
+SOX2,SOX2,Sox2,
+NANOG,NANOG,Nanog,
+FOXD3,FOXD3,Foxd3,forkhead box D3 [Source:MGI Symbol;Acc:MGI:1347473]
+TAF8,TBN,Taf8,TATA-box binding protein associated factor 8 [Source:MGI Symbol;Acc:MGI:1926879]
+TEAD2,TEF4,Tead2,TEA domain family member 2 [Source:MGI Symbol;Acc:MGI:104904]
+EIF1AX,EIF4C,Eif1ax,"eukaryotic translation initiation factor 1A, X-linked [Source:MGI Symbol;Acc:MGI:1913485]"
+CDX2,5.1.1,Cdx2,caudal type homeobox 2 [Source:MGI Symbol;Acc:MGI:88361]
+ASCL2,HASH2,Ascl2,achaete-scute family bHLH transcription factor 2 [Source:MGI Symbol;Acc:MGI:96920]
+EOMES,7.1.1,Eomes,eomesodermin [Source:MGI Symbol;Acc:MGI:1201683]
+GATA6,GATA6,Gata6,
+DSC2,DSC2,N/A,N/A
+LIFR,LIFR,Lifr,LIF receptor alpha [Source:MGI Symbol;Acc:MGI:96788]
+ERBB4,ERBB4,Erbb4,erb-b2 receptor tyrosine kinase 4 [Source:MGI Symbol;Acc:MGI:104771]

ground_truths/driver_regulators/GO_CELL_FATE_COMMITMENT.txt

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+GO_CELL_FATE_COMMITMENT
+ACVR1
+APC
+APC2
+AR
+ARHGEF2
+ARX
+ASCL1
+ATOH1
+BARHL2
+BATF
+BCL11B
+BCL2
+BMP2
+BMP4
+BMPR1A
+CASP3
+CDC42
+CDC73
+CDON
+CEBPB
+CHD5
+CTNNB1
+CTR9
+CTSL
+CYLD
+CYP26B1
+DBX1
+DHH
+DKK1
+DLL1
+DLL4
+DLX1
+DLX2
+DMRT3
+DMRTA2
+DOCK7
+DSCAML1
+EBF2
+ELF5
+EOMES
+EPAS1
+EPOP
+ERBB4
+ESRP1
+ETS2
+ETV2
+EVX1
+EYA1
+EYA2
+FEV
+FEZF2
+FGF10
+FGF13
+FGF2
+FGF8
+FGFR1
+FGFR2
+FKBP8
+FOXA1
+FOXA2
+FOXC2
+FOXG1
+FOXN1
+FOXN4
+FOXP3
+FZD7
+GAP43
+GAS1
+GATA1
+GATA2
+GATA3
+GATA4
+GATA5
+GATA6
+GBX1
+GCM1
+GDF3
+GDF7
+GLI2
+GLI3
+GLIS1
+GSC
+GSX1
+GSX2
+HES1
+HES5
+HEY2
+HNF1B
+HOXA11
+HOXA2
+HOXC10
+HOXD10
+ID2
+IFRD1
+IHH
+IL12B
+IL12RB1
+IL23A
+IL23R
+IL6
+IL7
+IRF4
+ISL1
+ISL2
+ITGB1
+JAG1
+JAG2
+KDM6B
+KLF4
+LATS1
+LBX1
+LEO1
+LHX3
+LMO4
+LOXL3
+LY9
+MCL1
+MEF2C
+MESP1
+MGA
+MIAT
+MIR1-1
+MIR1-2
+MIR133A1
+MIR133A2
+MIR19B1
+MIR19B2
+MIR206
+MIR208A
+MITF
+MNX1
+MTOR
+MYF5
+MYF6
+MYL2
+MYOD1
+MYOG
+MYT1L
+NANOG
+NEUROD1
+NEUROD4
+NEUROG1
+NFE2L1
+NKX2-1
+NKX2-2
+NKX2-5
+NKX6-1
+NKX6-2
+NODAL
+NOTCH1
+NOTCH2
+NOTCH3
+NOTCH4
+NR2E1
+NR2F2
+NRG1
+NRP1
+NTF4
+NTRK3
+OLIG1
+OLIG2
+OLIG3
+ONECUT1
+ONECUT2
+PAF1
+PAX2
+PAX6
+PAX7
+PDPN
+PITX1
+PML
+POU1F1
+POU3F2
+POU4F1
+POU5F1
+POU6F2
+PPARG
+PRDM1
+PRDM14
+PRKDC
+PROX1
+PRRX1
+PSEN1
+PTCH1
+PTCH2
+PTF1A
+RAB10
+RAG2
+RARA
+RBPJ
+RHOA
+ROR2
+RORA
+RORC
+RTF1
+RTF2
+RUNX2
+SATB2
+SFRP1
+SFRP2
+SH3PXD2B
+SHH
+SIX1
+SIX2
+SLAMF6
+SLAMF8
+SMAD1
+SMAD2
+SMAD4
+SMAD5
+SMO
+SOSTDC1
+SOX1
+SOX12
+SOX13
+SOX17
+SOX18
+SOX2
+SOX5
+SOX6
+SOX8
+SOX9
+SPDEF
+SPN
+SPRY2
+STAT3
+STAT6
+SUFU
+TAL1
+TBR1
+TBX1
+TBX10
+TBX15
+TBX18
+TBX19
+TBX2
+TBX20
+TBX21
+TBX22
+TBX3
+TBX4
+TBX5
+TBX6
+TBXT
+TCF3
+TCF7L2
+TEAD3
+TENM4
+TGFB1I1
+TGFBR1
+TLX3
+TOX
+TP53
+TRIM15
+WNT1
+WNT10A
+WNT10B
+WNT11
+WNT16
+WNT2
+WNT2B
+WNT3
+WNT3A
+WNT4
+WNT5A
+WNT5B
+WNT6
+WNT7A
+WNT7B
+WNT8A
+WNT8B
+WNT9A
+WNT9B
+WT1
+ZBTB7B
+ZFPM1
+ZNF445
+ZNF521

ground_truths/driver_regulators/GO_ENDODERM_DEVELOPMENT.txt

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+GO_ENDODERM_DEVELOPMENT
+HSBP1
+ONECUT1
+SMAD3
+MMP9
+COL4A2
+ITGA7
+LDB1
+SETD2
+SMAD4
+MMP15
+COL8A1
+LAMC1
+LEO1
+SOX2
+TBX20
+DUSP2
+INHBA
+RTF1
+NOTCH1
+HDAC1
+MMP2
+LHX1
+SMAD2
+BMPR1A
+DUSP1
+EPB41L5
+ZFP36L1
+GATA6
+LAMB3
+GATA4
+COL12A1
+NKX2-1
+FGF8
+ITGAV
+NODAL
+PELO
+BMP4
+LAMB1
+CTR9
+DUSP4
+FN1
+COL7A1
+SOX7
+NANOG
+NOG
+POU5F1
+MMP14
+VTN
+MMP8
+SOX17
+LAMA3
+KIF16B
+HMGA2
+MIXL1
+APELA
+DUSP5
+COL6A1
+COL11A1
+EXT1
+EOMES
+HOXC11
+MED12
+ITGB2
+BPTF
+ARC
+CDC73
+ITGA5
+PAF1
+ITGA4
+PAX9
+CTNNB1
+ITGB5