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88- ** Variants from population genetic studies** <br >
99We use human variants from the 1000 Genomes Project with allele ages estimated from the Genealogical Estimation of Variant Age (GEVA) approach.
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11- ## Summary of analysis workflow:
11+ ## Summary of analysis workflow
12121 . Preprocess 1000 Genomes variant data with ages from GEVA
13132 . Count binned variants, including for each continental population
14143 . Load mutation data and build Dirichlet-multinomial model
15154 . Estimate best-fit parental ages for variant spectrum in each bin
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17- ## Brief descriptions for folders and files in top-level of repository:
17+ ## Brief descriptions for folders and files in top-level of repository
1818### folders
1919- bootstraps/<br >
2020Recalculate estimates for each 100x100 double-bootstrap of model and variants
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