diff --git a/src/lib.rs b/src/lib.rs
index b90a340..16dbbfe 100644
--- a/src/lib.rs
+++ b/src/lib.rs
@@ -417,6 +417,8 @@ macro_rules! collect {
         impl $crate::Collect for $ty {
             #[inline]
             fn registry() -> &'static $crate::Registry {
+                #[allow(unexpected_cfgs)]
+                #[cfg_attr(asan, sanitize(address = "off"))]
                 static REGISTRY: $crate::Registry = $crate::Registry::new();
                 &REGISTRY
             }
@@ -512,6 +514,8 @@ macro_rules! __do_submit {
     (used={ $($used:tt)+ } $($value:tt)*) => {
         #[allow(non_upper_case_globals)]
         const _: () = {
+            #[allow(unexpected_cfgs)]
+            #[cfg_attr(asan, sanitize(address = "off"))]
             static __INVENTORY: $crate::Node = $crate::Node {
                 value: &{ $($value)* },
                 next: $crate::__private::UnsafeCell::new($crate::__private::Option::None),
diff --git a/tests/asan.rs b/tests/asan.rs
new file mode 100644
index 0000000..ad57c11
--- /dev/null
+++ b/tests/asan.rs
@@ -0,0 +1,90 @@
+use std::env;
+use std::ffi::OsString;
+use std::path::Path;
+use std::process::Command;
+
+#[rustversion::attr(not(nightly), ignore = "requires nightly")]
+#[cfg_attr(miri, ignore = "incompatible with miri")]
+#[cfg_attr(
+    not(any(
+        all(target_os = "macos",  any(target_arch = "x86_64", target_arch = "aarch64")),
+        all(target_os = "linux", any(target_arch = "x86_64", target_arch = "aarch64")),
+        all(target_os = "freebsd", target_arch = "x86_64"),
+        all(target_os = "fuchsia", any(target_arch = "x86_64", target_arch = "aarch64")),
+    )),
+    ignore = "Architecture does not support ASAN"
+)]
+#[test]
+fn asan_build() {
+    let manifest_dir = Path::new(env!("CARGO_MANIFEST_DIR"));
+    let fixture_dir = manifest_dir.join("tests/fixtures/asan");
+    let target_dir = manifest_dir.join("target/tests/asan");
+
+    let mut rustflags = OsString::from("-Zsanitizer=address -Cforce-frame-pointers=yes --cfg=asan");
+    if let Some(existing) = env::var_os("RUSTFLAGS") {
+        rustflags.push(" ");
+        rustflags.push(existing);
+    }
+
+    let build_target = detect_target_triple();
+
+    let cargo = env::var_os("CARGO").unwrap_or_else(|| OsString::from("cargo"));
+    let output = Command::new(cargo)
+        .arg("build")
+        .arg("-Zbuild-std")
+        .arg("--target")
+        .arg(build_target)
+        .current_dir(&fixture_dir)
+        .env("CARGO_TARGET_DIR", &target_dir)
+        .env("RUSTFLAGS", rustflags)
+        .output()
+        .expect("failed to run cargo build for ASan reproducer");
+
+    if !output.status.success() {
+        let stdout = String::from_utf8_lossy(&output.stdout);
+        let stderr = String::from_utf8_lossy(&output.stderr);
+        panic!(
+            "ASan reproducer build failed\nstatus: {}\nstdout:\n{}\nstderr:\n{}",
+            output.status, stdout, stderr,
+        );
+    }
+}
+
+fn detect_target_triple() -> String {
+    // Without build scripts we can't easily detect the target triple.
+    // Since the documentation says that ASAN is only available on a few targets,
+    // we do this ugly "detection" below, which avoids using a build script.
+    // https://doc.rust-lang.org/beta/unstable-book/compiler-flags/sanitizer.html#addresssanitizer
+    // aarch64-apple-darwin
+    // aarch64-unknown-fuchsia
+    // aarch64-unknown-linux-gnu
+    // x86_64-apple-darwin
+    // x86_64-unknown-fuchsia
+    // x86_64-unknown-freebsd
+    // x86_64-unknown-linux-gnu
+
+
+    if cfg!(target_os = "macos") {
+        if cfg!(target_arch = "aarch64") {
+            "aarch64-apple-darwin"
+        } else if cfg!(target_arch = "x86_64") {
+            "x86_64-apple-darwin"
+        } else {
+            panic!("unsupported macos architecture");
+        }
+    } else if cfg!(target_os = "linux") {
+        if cfg!(target_arch = "x86_64") && cfg!(target_env = "gnu") {
+            "x86_64-unknown-linux-gnu"
+        } else if cfg!(target_arch = "aarch64") && cfg!(target_env = "gnu") {
+            "aarch64-unknown-linux-gnu"
+        } else {
+            panic!("unsupported linux architecture");
+        }
+    } else if cfg!(target_os = "freebsd") && cfg!(target_arch = "x86_64") {
+        "x86_64-unknown-freebsd"
+    } else if cfg!(target_os = "fuchsia") && cfg!(target_arch = "aarch64") {
+        "aarch64-unknown-fuchsia"
+    } else {
+        panic!("unsupported target");
+    }.to_string()
+}
\ No newline at end of file
diff --git a/tests/fixtures/asan/Cargo.toml b/tests/fixtures/asan/Cargo.toml
new file mode 100644
index 0000000..e8311b8
--- /dev/null
+++ b/tests/fixtures/asan/Cargo.toml
@@ -0,0 +1,11 @@
+[package]
+name = "inventory-asan-reproducer"
+version = "0.0.0"
+edition = "2024"
+publish = false
+
+[dependencies]
+inventory = { path = "../../.." }
+
+[lib]
+path = "main.rs"
diff --git a/tests/fixtures/asan/main.rs b/tests/fixtures/asan/main.rs
new file mode 100644
index 0000000..3e35f6d
--- /dev/null
+++ b/tests/fixtures/asan/main.rs
@@ -0,0 +1,15 @@
+#![feature(sanitize)]
+
+struct Plugin(&'static str);
+
+inventory::collect!(Plugin);
+
+inventory::submit! {
+    Plugin("hello")
+}
+
+fn main() {
+    for plugin in inventory::iter::<Plugin> {
+        std::hint::black_box(plugin.0);
+    }
+}