+- *Negations, uncertainty, and hypothetical or conditional statements in medical texts.* In clinical notes, these cues may alter the interpretation of a medical situation, and it is crucial to correctly identify them and their scope. This thesis will focus on how well traditional systems (e.g., [Chapman et al., 2001](https://pubmed.ncbi.nlm.nih.gov/12123149/)) and large language models perform at identifying such linguistic cues and on their scope in clinical documentation (for comparable studies cf. [Su et al. 2024](https://pmc.ncbi.nlm.nih.gov/articles/PMC12092861) and [van Es et al. 2023](https://pmc.ncbi.nlm.nih.gov/articles/PMC9830789)). Students may either rely on existing gold-standard datasets ([BioScope](https://rgai.inf.u-szeged.hu/node/105), [NUBes](https://github.com/Vicomtech/NUBes-negation-uncertainty-biomedical-corpus), [IULA](https://eines.iula.upf.edu/brat//#/NegationOnCR_IULA/negation_iac_2_corr), ...) and emphasize modeling to improve performance, or create novel annotations from accessible clinical document corpora ([MIMIC](https://physionet.org/content/mimiciv/3.1/), [Cardio:DE](https://heidata.uni-heidelberg.de/dataset.xhtml?persistentId=doi:10.11588/data/AFYQDY), ...). Cross-lingual and cross-domain transfer learning may be included, given the scope of the thesis (cf. [Almudaifer et al. 2024](https://pubmed.ncbi.nlm.nih.gov/38849884/)).
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