diff --git a/lib/reline/io/ansi.rb b/lib/reline/io/ansi.rb
index 49068955d0..f2e9ecf56a 100644
--- a/lib/reline/io/ansi.rb
+++ b/lib/reline/io/ansi.rb
@@ -114,13 +114,15 @@ def with_raw_input
   end
 
   def inner_getc(timeout_second)
-    unless @buf.empty?
-      return @buf.shift
-    end
-    until @input.wait_readable(0.01)
+    while true
+      # @buf may change while handling signal, so we need to check it in each loop iteration.
+      return @buf.shift unless @buf.empty?
+      break if @input.wait_readable(0.01)
+
       timeout_second -= 0.01
       return nil if timeout_second <= 0
 
+      # handle_signal may call cursor_pos which modifies @buf
       Reline.core.line_editor.handle_signal
     end
     c = @input.getbyte