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_pathways/WP138.md

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title: Transcriptome analysis of newly established carboplatin-resistant ovarian
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cancer cell model reveals genes shared by drug resistance and drug-induced EMT
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(2023)
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- link: PMC8304581
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title: Site-Specific and Common Prostate Cancer Metastasis Genes as Suggested by
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Meta-Analysis of Gene Expression Data (2021)
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communities:
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- ONTOX
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description: 'Androgens, mainly testosterone and 5alpha-dihydrotestosterone (DHT)

_pathways/WP1530.md

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title: Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body
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Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype
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(2016)
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- link: PMC7913660
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title: A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene
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Expression (2021)
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communities:
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- ExRNA
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description: 'This is the first of two pathways which deals with the DNA damage response.

_pathways/WP1545.md

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- link: PMC12448840
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title: 'GNNenrich: a novel method for pathway enrichment analysis based on graph
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neural network (2025)'
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- link: PMC8743585
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title: Clinical and Molecular Characteristics of PRKACA L206R Mutant Cortisol-Producing
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Adenomas in Korean Patients (2021)
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communities:
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- ExRNA
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description: MicroRNA clusters involved in de DNA damage response. Genes they regulated

_pathways/WP179.md

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title: Genes whose expressions in the primary lung squamous cell carcinoma are able
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to accurately predict the progression of metastasis through lymphatic system,
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inferred from a bioinformatics analyses (2023)
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- link: PMC8304581
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title: Site-Specific and Common Prostate Cancer Metastasis Genes as Suggested by
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Meta-Analysis of Gene Expression Data (2021)
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communities:
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- CPTAC
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- ONTOX

_pathways/WP185.md

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- link: PMC4065073
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title: Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin
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complex reveals multiple functions within the podocyte (2014)
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- link: PMC8037168
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title: Distinct miRNA Signatures and Networks Discern Fetal from Adult Erythroid
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Differentiation and Primary from Immortalized Erythroid Cells (2021)
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communities:
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- CPTAC
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- ONTOX

_pathways/WP1984.md

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title: Transcriptome analysis of newly established carboplatin-resistant ovarian
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cancer cell model reveals genes shared by drug resistance and drug-induced EMT
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(2023)
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- link: PMC8304581
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title: Site-Specific and Common Prostate Cancer Metastasis Genes as Suggested by
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Meta-Analysis of Gene Expression Data (2021)
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communities: []
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description: This pathway incorporates the most important proteins for breast cancer.
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The Rp score from the Connectivity-Maps (C-Maps) webserver was used to determine

_pathways/WP1991.md

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- link: PMC12223304
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title: 'Causal role of immunophenotypes in HIV-1 acquisition: insights from Mendelian
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randomization analysis (2025)'
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- link: PMC8743585
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title: Clinical and Molecular Characteristics of PRKACA L206R Mutant Cortisol-Producing
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Adenomas in Korean Patients (2021)
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communities:
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- ExRNA
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description: Smooth muscle cells exhibit a unique plasticity, in that they are able

_pathways/WP2075.md

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- link: PMC12424221
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title: Stabilizing the retromer complex rescues synaptic dysfunction and endosomal
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trafficking deficits in an Alzheimer's disease mouse model (2025)
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- link: PMC8595495
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title: Thyroarytenoid muscle gene expression in a rat model of early-onset Parkinson’s
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disease (2021)
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description: 'This pathway displays current genes, proteolytic events and other processes
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associated with the progression of Alzheimer''s disease. This pathway was adapted
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from KEGG on 10/7/2011. Note: mitochondrial associated genes Cx I through Cx V are

_pathways/WP2249.md

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- link: PMC4553261
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title: Integration of extracellular RNA profiling data using metadata, biomedical
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ontologies and Linked Data technologies (2015)
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- link: PMC8743585
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title: Clinical and Molecular Characteristics of PRKACA L206R Mutant Cortisol-Producing
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Adenomas in Korean Patients (2021)
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communities:
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- CPTAC
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- Diseases

_pathways/WP231.md

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- link: PMC12048486
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title: Single-cell profiling unveils a geroprotective role of Procyanidin C1 in
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hematopoietic immune system via senolytic and senomorphic effects (2025)
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- link: PMC7913660
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title: A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene
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Expression (2021)
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communities:
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- ONTOX
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description: Tumor necrosis factor alpha (TNFα) is a proinflammatory cytokine involved

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