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_pathways/WP1539.md

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title: Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body
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Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype
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(2016)
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- link: PMC12891642
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title: Plasma exosomal hsa-miR-339-5p is associated with NOD-like receptor family
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CARD domain-containing 5 in heart failure with reduced ejection fraction (2026)
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communities:
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- ONTOX
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- PancCanNet

_pathways/WP2034.md

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title: Unraveling the genetic links between obesity or insulin resistance and breast
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cancer through the impact of CD295 and ITLN1 SNPs with DNA damage in a case-controlled
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study with bioinformatics analysis (2025)
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- link: PMC12891642
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title: Plasma exosomal hsa-miR-339-5p is associated with NOD-like receptor family
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CARD domain-containing 5 in heart failure with reduced ejection fraction (2026)
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communities: []
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description: 'Leptin is a peptide hormone mainly synthesised and secreted from adipocytes.
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It is also expressed in other tissues including placenta, stomach and skeletal muscle.

_pathways/WP2369.md

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- link: PMC6993862
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title: Proteostasis regulators modulate proteasomal activity and gene expression
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to attenuate multiple phenotypes in Fabry disease (2020)
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- link: PMC12891642
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title: Plasma exosomal hsa-miR-339-5p is associated with NOD-like receptor family
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CARD domain-containing 5 in heart failure with reduced ejection fraction (2026)
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communities:
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- ONTOX
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description: Histones can undergo many post-translational modifications that are involved

_pathways/WP2435.md

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- link: PMC12106470
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title: 'Glypican-3 regulated epithelial mesenchymal transformation-related genes
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in osteosarcoma: based on comprehensive tumor microenvironment profiling (2025)'
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- link: PMC12891642
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title: Plasma exosomal hsa-miR-339-5p is associated with NOD-like receptor family
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CARD domain-containing 5 in heart failure with reduced ejection fraction (2026)
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communities: []
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description: 'Quercetin is a flavonoid that is widely distributed in nature. In this
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pathway, its dual nature is depicted. On the one hand, it is capable of exerting

_pathways/WP2864.md

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Phase 3 (2020)
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- link: PMC6961668
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title: The double dealing of cyclin D1 (2020)
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- link: PMC12891642
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title: Plasma exosomal hsa-miR-339-5p is associated with NOD-like receptor family
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CARD domain-containing 5 in heart failure with reduced ejection fraction (2026)
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communities:
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- ExRNA
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description: Results of pathway analysis of apoptosis-related genes in OVCAR3 cells

_pathways/WP3932.md

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- link: PMC12652001
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title: Integrative Bioinformatics Analysis Reveals Key Regulatory Genes and Therapeutic
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Targets in Ulcerative Colitis Pathogenesis (2025)
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- link: PMC12891642
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title: Plasma exosomal hsa-miR-339-5p is associated with NOD-like receptor family
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CARD domain-containing 5 in heart failure with reduced ejection fraction (2026)
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communities:
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- CPTAC
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- ONTOX

_pathways/WP5300.md

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- link: PMC12004383
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title: Proteomics Analysis of Porcine Endometrial Cell-Derived Extracellular Vesicles
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Involved in Embryo Attachment (2025)
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- link: PMC12891642
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title: Plasma exosomal hsa-miR-339-5p is associated with NOD-like receptor family
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CARD domain-containing 5 in heart failure with reduced ejection fraction (2026)
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communities: []
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description: Schematic representation of TROP2 mediated signaling mechanism in different
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types of cancers

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