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_pathways/WP1253.md

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- link: PMC11984350
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title: 'GeneSetCart: assembling, augmenting, combining, visualizing, and analyzing
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gene sets (2025)'
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- link: PMC10910737
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title: Prodromal Parkinson disease signs are predicted by a whole-blood inflammatory
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transcriptional signature in young Pink1-/- rats (2024)
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communities: []
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description: Adapted from Raza et al. (2008). This pathway is initiated by IFNG binding
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to its receptor and a subsequent phosphorylation cascade involving a number of the

_pathways/WP1269.md

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in incised wound in skeletal muscle for wound aging (2016)
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- link: PMC3885437
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title: A provisional gene regulatory atlas for mouse heart development (2014)
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- link: PMC10910737
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title: Prodromal Parkinson disease signs are predicted by a whole-blood inflammatory
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transcriptional signature in young Pink1-/- rats (2024)
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description: Complete fatty acid beta-oxidation pathway for saturated and unsaturated
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fatty acids, developed and curated internally by BiGCaT Bioinformatics. This pathway
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was previously split into three parts plus a meta file for statistics. If you still

_pathways/WP179.md

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- link: PMC11539153
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title: Identification of key signaling pathways and novel computational drug target
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for oral cancer, metabolic disorders and periodontal disease (2024)
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- link: PMC10853805
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title: 'HetFCM: functional co-module discovery by heterogeneous network co-clustering
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(2024)'
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communities:
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- CPTAC
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- ONTOX

_pathways/WP18.md

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Marathon Mice (DUhTP) Reveals Higher Sterol Regulatory Element-Binding Protein
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(SREBP) Related mRNA Expression in the Liver and Higher Serum Levels of Progesterone
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(2016)
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- link: PMC10910737
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title: Prodromal Parkinson disease signs are predicted by a whole-blood inflammatory
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transcriptional signature in young Pink1-/- rats (2024)
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communities: []
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description: 'The enzymatic process that produces heme is porphyrin synthesis. The
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process is highly conserved across biology. In humans, this pathway serves almost

_pathways/WP1984.md

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- link: PMC8304581
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title: Site-Specific and Common Prostate Cancer Metastasis Genes as Suggested by
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Meta-Analysis of Gene Expression Data (2021)
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- link: PMC10853805
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title: 'HetFCM: functional co-module discovery by heterogeneous network co-clustering
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(2024)'
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communities: []
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description: This pathway incorporates the most important proteins for breast cancer.
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The Rp score from the Connectivity-Maps (C-Maps) webserver was used to determine

_pathways/WP2007.md

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- link: 10.1038/s41598-024-70629-7
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title: The differential expression of adipose tissue genes in short, medium and
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long-term periods after bariatric surgery (2024)
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- link: PMC10913609
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title: Identification of biomarkers and pathways for the SARS-CoV-2 infections in
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obstructive sleep apnea patients based on machine learning and proteomic analysis
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(2024)
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communities:
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- Micronutrients
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description: During pregnancy, iron is transported from mother to fetus across the

_pathways/WP2018.md

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title: 'A Practical Strategy for Exploring the Pharmacological Mechanism of Luteolin
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Against COVID-19/Asthma Comorbidity: Findings of System Pharmacology and Bioinformatics
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Analysis (2024)'
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- link: PMC11265978
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title: 'Large-scale proteomics in the first trimester of pregnancy predict psychopathology
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and temperament in preschool children: an exploratory study (2024)'
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communities: []
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description: 'RANKL (Receptor activator of nuclear factor-kappa B ligand), RANK (Receptor
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activator of nuclear factor-kappa B) and the natural decoy receptor of RANKL, OPG

_pathways/WP2037.md

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- link: PMC11960538
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title: 'Multiomics reveal key inflammatory drivers of severe obesity: IL4R, LILRA5,
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and OSM (2025)'
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- link: PMC11265978
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title: 'Large-scale proteomics in the first trimester of pregnancy predict psychopathology
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and temperament in preschool children: an exploratory study (2024)'
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communities: []
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description: 'Prolactin (PRL), a pleiotropic polypeptide hormone, mostly secreted
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by the lactotrophic cells of anterior pituitary gland and to a lesser extent expressed

_pathways/WP2064.md

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- link: PMC12854766
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title: Hierarchical Mechanistic Modeling of Complex Toxicity Endpoints from Public
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Concentration-Response Data (2026)
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- link: PMC11265978
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title: 'Large-scale proteomics in the first trimester of pregnancy predict psychopathology
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and temperament in preschool children: an exploratory study (2024)'
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communities:
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- ONTOX
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description: 'Gene regulatory network model of cranial neural crest cell (CNCC) development,

_pathways/WP2118.md

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- link: PMC9473477
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title: 'Network-Based Data Analysis Reveals Ion Channel-Related Gene Features in
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COVID-19: A Bioinformatic Approach (2022)'
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- link: PMC11265978
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title: 'Large-scale proteomics in the first trimester of pregnancy predict psychopathology
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and temperament in preschool children: an exploratory study (2024)'
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- link: PMC10816043
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title: 'Whole-Exome Screening and Analysis of Signaling Pathways in Multiple Endocrine
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Neoplasia Type 1 Patients with Different Outcomes: Insights into Cellular Mechanisms
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and Possible Functional Implications (2024)'
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communities: []
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description: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited
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heart disease that may result in arrhythmia, heart failure, and sudden death. Hallmark

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