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aaronwagen/Pericardial_fat_gwas_coloc

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Background

This repository contains scripts used to perform a colocalisation analysis using the pericardial fat GWAS and tissue eQTLs from GTEx v8.

Citation

If you use any of the code or data from this repository, please cite our paper. Further, if you use any of the software used within this repository (e.g. coloc, colochelpR, etc.) please make sure to cite the software appropriately.

License

The code in this repository is released under an MIT license. This repository is distributed in the hope that it will be useful to the wider community, but without any warranty of any kind. Please see the LICENSE file for more details.

Code contents

The workflow and analysis, including utilisation of any scripts, is described in analyse_pericard_fat_gwas_coloc.Rmd.

It can be view interactively at: https://aaronwagen.github.io/pat_gwas_gtex_coloc

Within this repository you will otherwise find:

Directory Description
docs Contains all .Rmds and their corresponding .htmls describing analyses performed for this project.
logs For any scripts that were run outside of an .Rmd (e.g. scripts from the scripts directory), a log file was recorded and can be accessed here.
manuscript Figures and tables produced for the manuscript.
processed_data Results from all analyses.
scripts Contains analysis scripts.

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Colocalisation analysis between pericardial fat GWAS and gene expression in GTEx8.

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