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drimransarmad/README.md

Dr. Imran Sarmad

PhD Statistical Consultant | Advanced Quantitative Modeling (R, Mplus)

I help researchers, academic authors, doctoral candidates, and organizations turn complex data into statistically sound, interpretable, and publication-ready results.

My work focuses on selecting defensible analytical strategies, evaluating assumptions carefully, and producing results that can hold under peer review, supervisor review, or stakeholder scrutiny.

Core Areas

  • Latent Profile Analysis (LPA) and Latent Class Analysis (LCA)
  • Structural Equation Modeling (SEM) and Confirmatory Factor Analysis (CFA)
  • Mixture modeling, covariates, and distal outcomes
  • Causal inference and observational-study interpretation
  • Clinical, real-world evidence (RWE), and health-research modeling
  • HEOR/HTA, cost-effectiveness analysis, and uncertainty-based decision modeling
  • Econometrics, simulation, and statistical validation

Tools

  • Statistical tools: R, Mplus, Python, Stata, SPSS
  • Applied strengths: Reproducible statistical computing, interpretable predictive modeling, validation, and simulation-based decision analysis

Selected Quantitative Modeling Projects

Predicting 30-Day Hospital Readmission Among Patients With Diabetes

A reproducible clinical/RWE predictive-modeling workflow emphasizing patient-level leakage prevention, protected test-set evaluation, benchmark comparison, probability calibration, and clinically cautious risk interpretation.

Probabilistic Cost-Effectiveness Analysis for Health Technology Assessment

A transparent HEOR/HTA decision-modeling workflow comparing two strategies through expected costs and QALYs, incremental analysis, net monetary benefit, Monte Carlo probabilistic sensitivity analysis, a cost-effectiveness plane, a CEAC, scenario analysis, and reproducible exports.

Estimating the Effect of Early Right Heart Catheterization on 30-Day Mortality

A reproducible clinical/RWE causal-inference workflow using observational data, stabilized IPTW, doubly robust AIPW, overlap diagnostics, covariate-balance assessment, bootstrap uncertainty analysis, and sensitivity checks.

Survival and Competing-Risk Analysis for Clinical Research

A reproducible clinical time-to-event workflow using Kaplan–Meier estimation, Cox proportional-hazards modeling, Schoenfeld-residual diagnostics, covariate-standardized survival curves, Aalen–Johansen cumulative incidence, cause-specific hazard modeling, and competing-risk sensitivity analysis.

Longitudinal Bilirubin Trajectories Using Linear Mixed-Effects Models

A reproducible longitudinal clinical modeling workflow using repeated serum bilirubin measurements from 312 patients. The project includes data-integrity auditing, patient-specific random intercepts and slopes, quadratic time modeling, adjusted trajectory prediction, residual diagnostics, and focused sensitivity analyses.

Bayesian Evidence Synthesis for Comparative Treatment Effectiveness

A reproducible Bayesian hierarchical evidence-synthesis workflow using mortality outcomes from 22 randomized clinical trials comparing beta-blocker therapy with control after myocardial infarction. The project includes conventional meta-analysis benchmarks, arm-level binomial modeling, prior-predictive and posterior-predictive checks, convergence diagnostics, between-study heterogeneity assessment, partially pooled trial-specific effects, future comparable-trial prediction, and prior-sensitivity analysis.

Professional Links

Pinned Loading

  1. diabetes-readmission-prediction-python diabetes-readmission-prediction-python Public

    Leakage-safe prediction of 30-day hospital readmission among patients with diabetes using calibrated, interpretable machine-learning models in Python.

    Jupyter Notebook

  2. hta-probabilistic-cost-effectiveness-python hta-probabilistic-cost-effectiveness-python Public

    Illustrative HTA-style probabilistic cost-effectiveness analysis using Python, Monte Carlo PSA, decision uncertainty, CEAC, scenario analysis, and reproducible exports.

    Jupyter Notebook

  3. causal-inference-rwe-python causal-inference-rwe-python Public

    Reproducible clinical/RWE causal-inference workflow estimating the effect of early right heart catheterization on 30-day mortality using IPTW, doubly robust AIPW, overlap diagnostics, sensitivity a…

    Jupyter Notebook

  4. survival-competing-risk-clinical-python survival-competing-risk-clinical-python Public

    Reproducible clinical survival and competing-risk analysis using Kaplan–Meier estimation, Cox modeling, Aalen–Johansen cumulative incidence, and Python.

    Jupyter Notebook

  5. longitudinal-bilirubin-mixed-effects-python longitudinal-bilirubin-mixed-effects-python Public

    Reproducible longitudinal clinical modeling of serum bilirubin trajectories using linear mixed-effects models in Python.

    Jupyter Notebook

  6. bayesian-evidence-synthesis-treatment-effectiveness-python bayesian-evidence-synthesis-treatment-effectiveness-python Public

    Reproducible Bayesian hierarchical evidence synthesis of mortality outcomes across beta-blocker trials, with heterogeneity assessment, prior sensitivity, posterior diagnostics, and partial pooling.

    Jupyter Notebook