Skip to content
View e-south's full-sized avatar

Block or report e-south

Block user

Prevent this user from interacting with your repositories and sending you notifications. Learn more about blocking users.

You must be logged in to block users.

Maximum 250 characters. Please don't include any personal information such as legal names or email addresses. Markdown supported. This note will be visible to only you.
Report abuse

Contact GitHub support about this user’s behavior. Learn more about reporting abuse.

Report abuse
e-south/README.md

Eric J. South

Systems, synthetic, and computational biologist at Boston University's Biological Design Center.

PhD candidate in the Dunlop Lab.

Email LinkedIn Google Scholar X Bluesky


Featured Work

dnadesign

dnadesign repository dnadesign data

dnadesign is a modular bioinformatics toolkit for biological sequence design.

dense-arrays

dense-arrays repository dense-arrays paper dense-arrays docs

dense-arrays is a library for designing double-stranded nucleotide sequences with densely packed DNA-protein binding sites.

reader

reader repository reader docs

reader is a toolkit for organizing experiment directories and running configuration-driven analysis pipelines on structured assay data.


Selected Experience

  • Boston University Biological Design Center (2020-present): PhD candidate developing genetic circuits, high-throughput functional assays, and DNA sequence-to-expression models to steer cell physiology in synthetic biology applications.
  • LanzaTech / EBRC (2022): Contributed to pooled DNA library design, high-throughput screening, next-generation sequencing, and biosensor workflows for gas-fermenting strains.
  • Imperial College London / Francis Crick Institute (2018-2020): Built a lab automation-enabled co-culture screening platform and an R analysis pipeline to map cross-feeding across an auxotrophic yeast knockout library.
  • SRI International / Center for Macromolecular Bioscience (2017-2018): Maintained mammalian cell cultures and evaluated peptide drug candidates in non-small cell lung cancer models using flow cytometry and Western blotting.

Selected Publications

Pinned Loading

  1. dense-arrays dense-arrays Public

    We introduce a computational technique that efficiently assembles sets of DNA-protein binding sites into dense, contiguous stretches of double-stranded DNA.

    Python

  2. dnadesign dnadesign Public

    A collection of Python modules and data analysis pipelines, all related to DNA sequence design.

    Python

  3. reader reader Public

    Command-line workbench for experimental data.

    Python

  4. dnadesign-data dnadesign-data Public

    This repository contains datasets, such as RegulonDB, EcoCyc, primary literature data.

    Python

  5. deg2tfbs deg2tfbs Public

    Pipeline for differential expression analysis (DEGs), transcription factor mapping, and TFBS identification.

    Python

  6. CIDARLAB/ibis CIDARLAB/ibis Public

    Graph-based Datastructure Library for Genetic and Boolean Circuits.

    Python 1 2