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Update Who_has_an_OpenSPIM.md
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Who_has_an_OpenSPIM.md

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- 3-D mouse
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# OsloSPIM at the University of Oslo, Norway
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We use our OpenSPIM to study how early mammalian embryo models (using so-called mouse gastruloids) grow and develop, and how the first organs form. Especially, we are interested in how cells self-organize and orchestrate their motion to form tissue. To explain the underpinning dynamics, we couple our experiments with 3D simulations. To fully utilize light-sheet imaging, we also study collective cell migration and how nerve cells make new connections in live zebrafish, and we study the cells' own recycling system (autophagy) in Drosophila larvae.
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{% include image src="OsloSPIM__OpenSPIM.jpg" width="100%" caption="a) Schematic overview of the OsloSPIM setup. b) Water at physiological temperature flows through channels in the viewing chamber. c) The sample holder has gears to ensure slip free rotation. CAD-files repository: https://doi.org/10.17605/OSF.IO/GRK2W" %}
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We use our OpenSPIM to study how early mammalian embryo models (using so-called mouse gastruloids) grow and develop, and how the first organs form. Especially, we are interested in how cells self-organize and orchestrate their motion to form tissue. To explain the underpinning dynamics, we couple our experiments with 3D simulations. To fully utilize light-sheet imaging, we also study collective cancer cell migration and how nerve cells make new connections in live zebrafish, and we study the cells' own recycling system (autophagy) in Drosophila larvae.
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https://www.uio.no/ritmo/english/people/postdoctoral-fellows/endrejm/index/
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- Media exchange: To provide fresh oxygen and nutrients to the 3D cell cultures, the media can be exchanged continually.
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