A Vue 3 + TypeScript application that visualizes medication concentration levels over time. Input prescription details and the app generates accurate line graphs showing peak and trough concentrations across your specified timeframe. Available as a web app or a standalone desktop application via Tauri.
Your data stays on your device. All prescription data is stored locally — in your browser's localStorage when using the web app, or on-disk within the desktop application. Nothing is sent to a server. There are no accounts, no cloud sync, and no telemetry. You own your data completely.
- Pharmacokinetic curve visualization — one-compartment first-order absorption model with multi-dose accumulation
- Prescription management — create, edit, delete, duplicate, drag-to-reorder, and export/import prescriptions (JSON)
- Multi-drug comparison — overlay multiple medications on a single graph
- PK summary table — peak time, peak concentration, trough time, and trough concentration for each dose
- Auto-extending timeframe — intelligent graph duration based on half-lives (24–2520 hours), with manual override
- Clock time X-axis — toggle between elapsed hours and wall-clock time (HH:MM) display
- Titration & taper schedules — build multi-step dose schedules with preset templates, comparison overlay, and summary table with steady-state warnings
- Schedule export/import — share and back up schedules as JSON files
- Downloadable graphs — export as PNG images
- Dark mode — full dark mode support with WCAG AA contrast compliance
- Keyboard-accessible navigation — tab-based navigation with aria-labels and help tooltips
- Desktop app — native cross-platform builds via Tauri v2 (macOS, Windows, Linux)
- Metabolite visualization — optional display of active metabolite concentration curves (work in progress, parameters being refined)
- Privacy-first — zero network requests, no accounts, no telemetry
Download the latest release for your platform from the Releases page:
| Platform | Download |
|---|---|
| macOS | .dmg (universal binary — works on Intel and Apple Silicon) |
| Windows | .exe installer |
| Linux | .AppImage or .deb |
Open the downloaded file and follow your platform's standard install process.
For building from source or contributing, see DEVELOPER.md.
- Open the app in your browser or launch the desktop application
- Enter prescription details:
- Drug name (e.g., "Ibuprofen", "Amoxicillin")
- Dose per administration (in mg or units)
- Frequency (once daily, bid, tid, qid, every 6/8/12 hours, or custom)
- Dosing times (what time of day you take it)
- Half-life (from pharmacy insert)
- Time to peak absorption (Tmax, from insert)
- Absorption time (uptake)
- View the graph showing:
- Peak and trough concentration points
- Accumulation over multiple doses
- Normalized relative concentration (0–1 scale)
- PK summary table with per-dose milestones
- Save and compare: Save prescriptions locally and overlay multiple drugs on the same graph
- Export/Import: Export prescriptions or schedules as JSON, import them back, or download graphs as PNG images
- Titration/Taper schedules: Build multi-step dose schedules from presets or custom configurations, compare schedules side-by-side, and review summary tables
The app uses a one-compartment first-order absorption model:
C(t) = Dose × [ka/(ka - ke)] × (e^(-ke×t) - e^(-ka×t))
Where:
ka= absorption rate constant (derived from uptake time)ke= elimination rate constant (derived from half-life)t= time since dose
Multi-dose accumulation sums contributions from each scheduled dose, then normalizes the total curve so the highest concentration point = 1.0. Steady-state patterns emerge after approximately 5 half-lives.
A fallback formula (C(t) = Dose × ka × t × e^(-ke×t)) is used when ka and ke are nearly equal (|ka - ke| < 0.001), avoiding numerical instability.
For drugs with active metabolites, the app supports an optional sequential metabolism model using a one-compartment parent-to-metabolite conversion. Metabolite curves are displayed as dashed lines alongside the parent drug curve. This feature is actively being developed — metabolite parameters (conversion fraction, elimination half-life) and their visualization are still being refined and may change between releases.
Important: This app visualizes approximate concentration curves for educational and visualization purposes only. It is not for medical dosing decisions.
All data created in Pharmacokinetics Grapher stays on your device:
| Platform | Where data lives | How to clear it |
|---|---|---|
| Web app (browser) | Browser localStorage under the app's origin |
Clear site data in browser settings, or use the app's delete functions |
| Desktop app (Tauri) | App data directory on your local filesystem | Uninstall the app, or delete its data folder |
- No server communication. The app makes zero network requests. It runs entirely client-side.
- No accounts or sign-in. There is nothing to register for.
- No analytics or telemetry. No usage data is collected or transmitted.
- Portable. Your prescriptions live where you run the app. If you clear your browser data or uninstall the desktop app, the data is gone.
This app is for visualization and educational purposes only.
This application demonstrates pharmacokinetic principles using simplified models. It is not intended for medical dosing decisions. Actual drug concentrations vary significantly based on individual factors (age, weight, liver/kidney function, food interactions, other medications, etc.).
Always follow prescriptions written by licensed healthcare providers and consult with a pharmacist for any medication questions.
This project is open source and available for educational purposes.
This project was built with assistance from AI tools:
- Claude Opus 4.6 (Anthropic) — coding and implementation
- Gemini (Google) — planning collaboration and image generation
- Codex GPT 5.2 (OpenAI) — planning collaboration