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Segmentation of Cornea Cells using U-Net Architecture

  • Segmented the microscopic images of corneal endothelium cells and labeled each pixel as cell interior, cell border, or background.
  • Developed and trained a 32x32 image patch-segmenting 24-layer U-Net model to an accuracy of 80% in training and 72% in validation.
  • Reconstructed test segments by applying a sliding window operation on 500x500 test images while employing a 32x32 U-Net model.
  • Plotted the ROC Curves and got an area under the curve (AUC) of 0.869 with the training set patches and 0.839 with the testing set patches.

NOTE: Open Final_Project.ipynb to see the full training, testing & evaluation processes.

The Network Architecture:

U-Net_Network

Segmentation & Reconstruction Quality:

Segmentation_Quality

Segmented 32x32 Patches output from the network:

Segmented_Patches

ROC Curves:

Training:

ROC_Training

Testing:

ROC_Testing

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Segmentation of microscopic images of corneal endothelium cells as cell interior, cell border, or background.

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